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A hold-and-feed mechanism drives directional DNA loop extrusion by condensin. Shaltiel IA, Datta S, Lecomte L, Hassler M, Kschonsak M, Bravo S, Stober C, Ormanns J, Eustermann S, Haering CH. Science. 2022 Jun 3;376(6597):1087-1094. doi: 10.1126/science.abm4012. Epub 2022 Jun 2.