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A preclinical model of cutaneous melanoma based on reconstructed human epidermis. Leikeim A, Wußmann M, Schmidt FF, Neto NGB, Benz F, Tiltmann K, Junger C, Monaghan MG, Schilling B, Groeber-Becker FK. Sci Rep. 2022 Sep 29;12(1):16269. doi: 10.1038/s41598-022-19307-0.
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Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation. Lotz C, Kiesewetter L, Schmid FF, Hansmann J, Walles H, Groeber-Becker F. Sci Rep. 2018 Oct 9;8(1):15049. doi: 10.1038/s41598-018-33118-2.
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A standardized method based on pigmented epidermal models evaluates sensitivity against UV-irradiation. Schmid FF, Groeber-Becker F, Schwab S, Thude S, Walles H, Hansmann J. ALTEX. 2018;35(3):390-396. doi: 10.14573/altex.1712211. Epub 2018 Apr 13.
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Cross-linked Collagen Hydrogel Matrix Resisting Contraction To Facilitate Full-Thickness Skin Equivalents. Lotz C, Schmid FF, Oechsle E, Monaghan MG, Walles H, Groeber-Becker F. ACS Appl Mater Interfaces. 2017 Jun 21;9(24):20417-20425. doi: 10.1021/acsami.7b04017. Epub 2017 Jun 9.
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Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II). Groeber F, Schober L, Schmid FF, Traube A, Kolbus-Hernandez S, Daton K, Hoffmann S, Petersohn D, Schäfer-Korting M, Walles H, Mewes KR. Toxicol In Vitro. 2016 Oct;36:254-261. doi: 10.1016/j.tiv.2016.07.008. Epub 2016 Jul 17.
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A first vascularized skin equivalent as an alternative to animal experimentation. Groeber F, Engelhardt L, Lange J, Kurdyn S, Schmid FF, Rücker C, Mielke S, Walles H, Hansmann J. ALTEX. 2016;33(4):415-422. doi: 10.14573/altex.1604041. Epub 2016 May 15.
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Alternative methods for the replacement of eye irritation testing. Lotz C, Schmid FF, Rossi A, Kurdyn S, Kampik D, De Wever B, Walles H, Groeber FK. ALTEX. 2016;33(1):55-67. doi: 10.14573/altex.1508241. Epub 2015 Dec 2.
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